The NASA Twins Genome Study investigates the effects of spaceflight on somatic mutation accumulation by comparing genome-wide sequence data from a spaceflight astronaut and his Earth-bound twin. Utilizing advanced computational software on high performance computers, this study identifies and maps somatic mutations, with implications for understanding spaceflight-associated health risks, including cancer, neurodegeneration, and cardiovascular disease. The findings aim to bridge rodent and human space research, offering insights into tissue-specific pathophysiology, risk models, and potential therapeutic interventions.


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    Title :

    Somatic Mutation Analysis in Spaceflight: NASA Twins Genome Study


    Contributors:
    V. Stolc (author) / M. Karhanek (author) / D. J. Loftus (author)

    Publication date :

    2025


    Size :

    1 pages


    Type of media :

    Report


    Type of material :

    No indication


    Language :

    English




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