Pituitary levels of oxytocin (OT) and vasopressin (VP) were measured in rats exposed to 14 days of spaceflight (FLT) as well as in ground-based controls; one group synchronously maintained in flight-type cages with similar feeding schedules (SYN), one group in vivarium cages (VIV), and a group of tail suspended (SUS) animals. Flight rats had significantly less (p less than 0.05) pituitary OT and VP (4.48 +/- 0.31 and 7.48 +/- 0.53 mg hormone / mg protein, n = 5) than either the SYN (6.66 +/- 0..59 and 10.98 + 1.00, n = 5), VIV (6.14 +/- 0.40 and 10.98 +/- 0..81, n = 5) or SUS (5.73 +/- 0.24, n = 4) control groups, respectively. The reduced levels of pituitary OT and VP are similar to measurements made on rats from the previous 12.5 day Cosmos 1887 mission and appear to be a direct result of exposure to spaceflight.


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    Title :

    Experiment K-7-20: Pituitary Oxytocin and Vasopressin Content of Rats Flown on Cosmos 2044


    Contributors:
    Keil, L. (author) / Evans, J. (author) / Grindeland, R. (author) / Krasnov, I. (author)


    Publication date :

    1994-09-01


    Type of media :

    Miscellaneous


    Type of material :

    No indication


    Language :

    English




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