Closed-loop neural prostheses have been widely used as a therapeutic strategy for a range of neurological, inflammatory, and cardiac disorders. Vagus nerve stimulation has shown promising results for the monitoring and treatment of post-operation symptoms of heart transplant recipients. A prime candidate for selective control of vagal fibres is the microchannel neural interface (MNI), which provides a suitable environment for neural growth and enables effective control of the neural activity in a bidirectional system. This paper presents the design and simulation of an ASIC in 180-nm high-voltage CMOS technology, capable of concurrent stimulation and neural recording with artifact reduction in a seven-channel MNI. The analog front-end amplifies action potentials with a gain of 40 dB, presenting a common-mode rejection ratio of 81 dB at 1 kHz and a noise efficiency factor of 5.13 over the 300 Hz to 5 kHz recording bandwidth. A 42-V-compliant stimulation module operates concurrently and independently across the seven channels.


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    Title :

    A Bidirectional ASIC for Active Microchannel Neural Interfaces


    Contributors:

    Publication date :

    2022-10-24


    Remarks:

    In: 2022 29th IEEE International Conference on Electronics, Circuits and Systems (ICECS). IEEE: Glasgow, UK. (2022)


    Type of media :

    Paper


    Type of material :

    Electronic Resource


    Language :

    English



    Classification :

    DDC:    629




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