Closed-loop neural prostheses have been widely used as a therapeutic strategy for a range of neurological, inflammatory, and cardiac disorders. Vagus nerve stimulation has shown promising results for the monitoring and treatment of post-operation symptoms of heart transplant recipients. A prime candidate for selective control of vagal fibres is the microchannel neural interface (MNI), which provides a suitable environment for neural growth and enables effective control of the neural activity in a bidirectional system. This paper presents the design and simulation of an ASIC in 180-nm high-voltage CMOS technology, capable of concurrent stimulation and neural recording with artifact reduction in a seven-channel MNI. The analog front-end amplifies action potentials with a gain of 40 dB, presenting a common-mode rejection ratio of 81 dB at 1 kHz and a noise efficiency factor of 5.13 over the 300 Hz to 5 kHz recording bandwidth. A 42-V-compliant stimulation module operates concurrently and independently across the seven channels.


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    A Bidirectional ASIC for Active Microchannel Neural Interfaces


    Beteiligte:

    Erscheinungsdatum :

    24.10.2022


    Anmerkungen:

    In: 2022 29th IEEE International Conference on Electronics, Circuits and Systems (ICECS). IEEE: Glasgow, UK. (2022)


    Medientyp :

    Paper


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Klassifikation :

    DDC:    629




    ASIC für Sitzkomfortsysteme

    DÖRFLER ERICH / GEHLMANN RONNY | Europäisches Patentamt | 2021

    Freier Zugriff

    A reconfigurable spiking neural network digital ASIC simulation and implementation

    Van Sickle, Kevin / Abdel-Aty-Zohdy, Hoda | IEEE | 2009


    Bidirectional field compensated active antenna

    Wanner, Robert / Sobhy, Mohamed I. / Russer, Peter | Tema Archiv | 2007


    An ASIC Companion Microcontroller

    Mitchell, Ronald L. | SAE Technical Papers | 1987