Due to loss of tactile feedback the assessment of tumor margins during robotic surgery is based only on visual inspection, which is neither significantly sensitive nor specific. Here we demonstrate time-resolved fluorescence spectroscopy (TRFS) as a novel technique to complement the visual inspection of oral cancers during transoral robotic surgery (TORS) in real-time and without the need for exogenous contrast agents. TRFS enables identification of cancerous tissue by its distinct autofluorescence signature that is associated with the alteration of tissue structure and biochemical profile. A prototype TRFS instrument was integrated synergistically with the da Vinci Surgical robot and the combined system was validated in swine and human patients. Label-free and real-time assessment and visualization of tissue biochemical features during robotic surgery procedure, as demonstrated here, not only has the potential to improve the intraoperative decision making during TORS but also other robotic procedures without modification of conventional clinical protocols. ; publishedVersion


    Zugriff

    Download


    Exportieren, teilen und zitieren



    Titel :

    Autofluorescence lifetime augmented reality as a means for real-time robotic surgery guidance in human patients


    Beteiligte:

    Erscheinungsdatum :

    01.01.2019


    Anmerkungen:

    Scientific Reports 9 (2019)



    Medientyp :

    Aufsatz (Zeitschrift)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch



    Klassifikation :

    DDC:    629




    LANE GUIDANCE USING AUGMENTED REALITY

    TOMATSU NOBUYUKI / KASHIBA YUSUKE / DAI SIYUAN | Europäisches Patentamt | 2018

    Freier Zugriff

    Parking guidance system applying virtual reality/augmented reality

    YAN ZHEN | Europäisches Patentamt | 2020

    Freier Zugriff

    Augmented Reality Based Parking Guidance System

    LEE JUN SEO | Europäisches Patentamt | 2021

    Freier Zugriff

    Augmented Reality Based Parking Guidance System

    Europäisches Patentamt | 2022

    Freier Zugriff

    AUGMENTED REALITY BASED DRIVER GUIDANCE SYSTEM

    SALGIA UMANG / DESHMUKH VIBHOR / NAIR CHANTHU et al. | Europäisches Patentamt | 2020

    Freier Zugriff