The changes in erythropoiesis in astronauts caused by weightlessness was experimentally studied during the Spacelab 1 flight. Immediately after landing showed a mean decrease of 9,3 percent in the four astronauts. Neither hyperoxia nor an increase in blood phosphate caused the decrease. Red cell survival time and iron incorporation postflight were not significantly different from their preflight levels. Serum haptoglobin did not decrease, indicating that intravascular hemolysis was not a major cause of red cell mass change. An increase in serum ferritin after the second day of flight may have been caused by red cell breakdown early in flight. The space flight-induced decrease in red cell mass may result from a failure of erythropoesis to replace cells destroyed by the spleen soon after weightlessness is attained.


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    Titel :

    Hematology and biochemical findings of Spacelab 1 flight


    Beteiligte:
    Leach, Carolyn S. (Autor:in) / Chen, J. P. (Autor:in) / Crosby, W. (Autor:in) / Johnson, P. C. (Autor:in) / Lange, R. D. (Autor:in) / Larkin, E. (Autor:in) / Tavassoli, M. (Autor:in)

    Erscheinungsdatum :

    01.01.1988


    Medientyp :

    Sonstige


    Format :

    Keine Angabe


    Sprache :

    Englisch


    Schlagwörter :




    Spacelab flight operations

    Harlan, C. S. / Cress, G. H. / White, T. A. | NTRS | 1979


    Shuttle and Spacelab flight operations

    Oneill, J. W. | NTRS | 1982


    Shuttle And Spacelab Flight Operations

    O'Neill, John W. | SPIE | 1982