Abstract Samples of plasmid DNA were irradiated with pulsed 18.9 nm radiation originating from a Mo X-ray laser pumped in GRIP configuration at the LASERIX facility [1]. Surface doses of up to 500 kGray were delivered with a repetition rate of 10 Hz and average pulse energy of 200 nJ. The occurrence of single and double strand breaks not present in controls having undergone the same treatment except for the XRL irradiation can be seen as a clear effect of the XRL irradiation. This confirms the role of direct effects in DNA damages as previously seen with low energy ions [2, 3] and electrons.


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    Titel :

    Strand Breaks in DNA Samples Induced with LASERIX


    Beteiligte:
    Zielbauer, B. (Autor:in) / Habib, J. (Autor:in) / Kazamias, S. (Autor:in) / Guilbaud, O. (Autor:in) / Pittman, M. (Autor:in) / Ros, D. (Autor:in) / Hervé du Penhoat, M. -A. (Autor:in) / Touati, A. (Autor:in) / Sech, C. Le (Autor:in) / Porcel, E. (Autor:in)

    Erschienen in:

    X-Ray Lasers 2008 ; 7 ; 409-411


    Erscheinungsdatum :

    01.01.2009


    Format / Umfang :

    3 pages





    Medientyp :

    Aufsatz/Kapitel (Buch)


    Format :

    Elektronische Ressource


    Sprache :

    Englisch




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    Theoretical consideration of the chemical pathways for radiation-induced strand breaks

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    Heavy ion induced DNA double strand breaks in cells of E. coli

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